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Necroptosis-IN-3
$120 – $1,040
Products Details
Product Description
– Necroptosis-IN-3 (Compound 69) is a necroptosis inhibitor that inhibits TNF-α induced necroptosis[1]. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1[2].
Web ID
– HY-148454
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H17NOS
References
– [1]Junying Yuan, et al. Small molecule inhibitors of necroptosis. Patent US20120122889A1.|[2]Nigel Vicker, et al. Compound. Patent US20100120789A1.
CAS Number
– 547698-18-0
Molecular Weight
– 223.33
Compound Purity
– 99.77
SMILES
– O=C(C1CCCCC1)NCC2=CC=CS2
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– 11β-HSD;Necroptosis
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
