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Neamine (tetrahydrochloride)
SKU
HY-115349-Get quote
Category Reference compound
Tags Anti-infection, Bacterial, Cancer; Infection; Neurological Disease
Products Details
Product Description
– Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities[1][2].
Web ID
– HY-115349
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H30Cl4N4O6
References
– [1]Ya-Ping Liu, et al. Neamine Inhibits Growth of Pancreatic Cancer Cells in Vitro and in Vivo. J Huazhong Univ Sci Technolog Med Sci. 2016 Feb;36(1):82-87.|[2]R Ning, et al. Neamine Induces Neuroprotection After Acute Ischemic Stroke in Type One Diabetic Rats. Neuroscience. 2014 Jan 17;257:76-85.
CAS Number
– 15446-43-2
Molecular Weight
– 468.20
SMILES
– O[C@H]([C@H]([C@@H](C[C@@H]1N)N)O)[C@@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2N)O)O)CN.Cl.Cl.Cl.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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