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NCGC00244536
$132 – $2,520
Products Details
Product Description
– NCGC00244536 is a potent KDM4B inhibitor with an IC50 of 10 nM.
Web ID
– HY-101799
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H22N2O2
References
– [1]Duan L, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chem Biol. 2015 Sep 17;22(9):1185-96.
CAS Number
– 2003260-55-5
Molecular Weight
– 382.45
Compound Purity
– 99.58
SMILES
– O=C(NCCCC1=CC=CC=C1)C2=CC=CC(C3=CC(O)=C4N=CC=CC4=C3)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 36.67 mg/mL (ultrasonic)
Target
– Histone Demethylase
Isoform
– KDM4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.