Products Details

Product Description

– NCGC00188636 is a novel covalent pyruvate kinase (PYK) inhibitor. NCGC00188636 blocks nucleotide binding to the active site of pyruvate kinase. NCGC00188636 can be used for the research of the metabolism of many organisms and cell types.

Web ID

– HY-138825

Shipping

– Room temperature

Molecular Formula

– C14H9NO4S2

References

– [1]Hugh P Morgan, et al. A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase. Biochem J. 2012 Nov 15;448(1):67-72.

CAS Number

– 1039980-33-0

Molecular Weight

– 319.36

SMILES

– O=C(O)C1=CC=CC=C1SC(C2=C3C=CC=C2)=NS3(=O)=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Pyk2

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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