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NCD38 (TFA)
Products Details
Product Description
– NCD38 TFA is a LSD1-selective inhibitor[1][2].
Web ID
– HY-112304
Shipping
– Room temperature
Molecular Formula
– C37H37ClF3N3O4
References
– [1]G R Sareddy, et al. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017 Apr 27;36(17):2423-2434.|[2]Yosuke Ota , et al. Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors. Bioorg Med Chem. 2018 Feb 1;26(3):775-785.
Molecular Weight
– 680.16
SMILES
– O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C(NCC3=CC=CC(Cl)=C3)=O)CCCCN[C@H]4[C@H](C5=CC=CC=C5)C4.O=C(O)C(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Histone Demethylase
Pathway
– Epigenetics
Product type
– Reference compound
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