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NCB-0846
$90 – $940
Products Details
Product Description
– NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21 nM.
Web ID
– HY-100830
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H21N5O2
References
– [1]Masuda M, et al. TNIK inhibition abrogates colorectal cancer stemness. Nat Commun. 2016 Aug 26;7:12586.
CAS Number
– 1792999-26-8
Molecular Weight
– 375.42
Compound Purity
– 99.61
SMILES
– O[C@@H](CC1)CC[C@@H]1OC2=CC=CC(C=N3)=C2N=C3NC4=CC=C(N=CN5)C5=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 30 mg/mL
Target
– MAP4K;Wnt
Isoform
– MAP4K7/TNIK
Pathway
– MAPK/ERK Pathway;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
