Products Details

Product Description

– NBTIs-IN-6 is a bacterial topoisomerase inhibitor with certain antibacterial activity. Among them, the MIC90 for fluoroquinolone-resistant MRSA was 2 μg/mL[1].

Web ID

– HY-146816

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C25H27FN4O6

References

– [1]Antony Okumu, et al. Novel bacterial topoisomerase inhibitors derived from isomannide. Eur J Med Chem. 2020 Aug 1;199:112324. 

CAS Number

– 2422893-97-6

Molecular Weight

– 498.50

SMILES

– [H][C@]12OC[C@@H]([C@]1(OC[C@@]2(CCC3=C(C=NC4=CC=C(N=C43)OC)F)O)[H])NCC5=NC=C6OCCOC6=C5

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Topoisomerase

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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