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Products Details
Product Description
– Nav1.8-IN-2 (compound 35A) is a potent Nav1.8 inhibitor with an IC50 value of 0.4 nM. Nav1.8-IN-2 can be used for researching pain disorders, cough disorders, and acute and chronic itch disorders[1].
Web ID
– HY-143481
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H13Cl2F3N2O3
References
– [1]Sabnis RW. 2-Oxooxazolidine-5-carboxamides as Nav1.8 Inhibitors for Treating Pain Disorders, Cough Disorders, and Acute and Chronic Itch Disorders. ACS Med Chem Lett. 2022;13(3):334-335. Published 2022 Mar 1.
CAS Number
– 2756250-30-1
Molecular Weight
– 433.21
SMILES
– O=C([C@H]1OC(NC1)=O)N[C@@H](C2=CC=C(C=C2)Cl)C3=CC(C(F)(F)F)=C(C=C3)Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Isoform
– Nav1.8
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
