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Nav1.8-IN-1
SKU
HY-132133-1mg
Category Reference compound
Tags Inflammation/Immunology; Neurological Disease, Membrane Transporter/Ion Channel, Sodium Channel
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– Nav1.8-IN-1 (Compound 31) is a potent inhibitor of Na(v)1.8 sodium channel. Nav1.8-IN-1 has the potential for the research of inflammatory and neuropathic pain[1].
Web ID
– HY-132133
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H15ClF3N3O2
References
– [1]Kort ME, et al. Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. Bioorg Med Chem Lett. 2010;20(22):6812-6815.
CAS Number
– 1026822-49-0
Molecular Weight
– 421.80
SMILES
– O=C(C1=CC(C2=CC=C(Cl)C=C2)=CN=C1)NCC3=CC=CN=C3OCC(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sodium Channel
Isoform
– Nav1.8
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.