Naspm

$96$810

Products Details

Product Description

– Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

Web ID

– HY-12506

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C22H34N4O

Citations

– Cell Rep. 2023 Dec 3;42(12):113551.|iScience. 2023 Mar.|J Headache Pain. 2022 Aug 10;23(1):98.|Neuroscience. 2021 Sep 9;S0306-4522(21)00454-1.|Toxicol In Vitro. 2017 Oct;44:57-65. |Cell Rep. 2020 Nov 10;33(6):108369.

References

– [1]Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.

CAS Number

– 122306-11-0

Molecular Weight

– 370.53

Compound Purity

– 96.30

SMILES

– O=C(NCCCNCCCCNCCCN)CC1=C2C=CC=CC2=CC=C1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 10 mg/mL (ultrasonic)

Target

– iGluR

Isoform

– AMPA Receptor

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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