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Nampt activator-2
SKU
HY-148822-10 mg
Category Reference compound
Tags Metabolic Enzyme/Protease, NAMPT, Neurological Disease
$250 – $2,050
Products Details
Product Description
– Nampt activator-2 (compound 34) is a potent NAMPT activator, with EC50 of 0.023 μM. Nampt activator-2 shows moderate activity against CYP2C9 (0.060 μM), 2D6 (0.41 μM) and 2C19 (0.59 μM)[1].
Web ID
– HY-148822
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C17H15ClN4O3S
References
– [1]Pinkerton AB, et al. Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators. Bioorg Med Chem Lett. 2021 Jun 1;41:128007.
CAS Number
– 2237268-90-3
Molecular Weight
– 390.84
Compound Purity
– 98.80
SMILES
– O=C(NCC1=CNN=C1)NC2=CC=C(S(=O)(C3=CC=C(C=C3)Cl)=O)C=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– NAMPT
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.