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Products Details
Product Description
– Naloxonazine is a potent and selective opiate mu-1 antagonist that can also affect leishmania by regulating host coding function[1].
Web ID
– HY-137180
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C38H42N4O6
References
– [1]Géraldine De Muylder, et al. Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions. PLoS Negl Trop Dis. 2016 Dec 30;10(12):e0005234. |[2]Roberto Ciccocioppo, et al.  Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats. Neuropsychopharmacology. 2002 Sep;27(3):391-9.Â
CAS Number
– 82824-01-9
Molecular Weight
– 650.76
SMILES
– O[C@@]1(CC/2)[C@@]([C@](O3)([H])C2=NN=C(CC4)[C@@](OC5=C6O)([H])[C@]7(CCN8CC=C)C5=C(C=C6)C[C@]8([H])[C@@]74O)(CC9)C(C3=C%10O)=C(C=C%10)C[C@@]1([H])N9CC=C
Clinical Information
– No Development Reported
Research Area
– Infection; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Opioid Receptor;Parasite
Isoform
– Leishmania
Pathway
– Anti-infection;GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
