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Products Details
Product Description
– Nalidixic acid sodium salt, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria[1][2].
Web ID
– HY-B0398A
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C12H11N2NaO3
References
– [1]G Y LESHER,et al. 1,8-NAPHTHYRIDINE DERIVATIVES. A NEW CLASS OF CHEMOTHERAPEUTIC AGENTS. J Med Pharm Chem. 1962 Sep;91:1063-5.|[2]Anna FÃ brega, et al. Mechanism of Action of and Resistance to Quinolones. Microb Biotechnol
CAS Number
– 3374-05-8
Molecular Weight
– 254.22
SMILES
– O=C(C1=CN(CC)C2=NC(C)=CC=C2C1=O)O[Na]
Clinical Information
– Launched
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial;Topoisomerase
Isoform
– Quinolone;Topoisomerase
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
