Products Details

Product Description

– NAD+-13C5-1 is the 13C labeled NAD+[1]. NAD+ is a coenzyme composed of ribosylnicotinamide 5′-diphosphate coupled to adenosine 5′-phosphate by pyrophosphate linkage.

Web ID

– HY-B0445S1

Shipping

– Room temperature

Molecular Formula

– C16 13C5H27N7O14P2

References

– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70.|[3]Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92.|[4]Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12.

CAS Number

– 1859096-06-2

Molecular Weight

– 668.39

SMILES

– O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(O[13CH2][13C@H]2O[13C@]([N+]3=CC=CC(C(N)=O)=C3)([H])[13C@@H]([13C@@H]2O)O)([O-])=O)(O)=O)([H])N4C5=NC=NC(N)=C5N=C4

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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