N6,2′-O-Dimethyladenosine

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Products Details

Product Description

– N6,2′-O-Dimethyladenosine, a substrate of fat mass and obesity-associated gene (FTO), is a reversible modification widely occurred on varied RNA molecules. N6,2′-O-Dimethyladenosine can regulate obesity[1][2].

Web ID

– HY-101082

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C12H17N5O4

References

– [1]Ben-Haim MS, et, al. Dynamic regulation of N 6,2′-O-dimethyladenosine (m 6 Am) in obesity. Nat Commun. 2021 Dec 10;12(1):7185.|[2]Jiang J, et, al. m6AmPred: Identifying RNA N6, 2′-O-dimethyladenosine (m 6 A m) sites based on sequence-derived information. Methods. 2021 Feb 2;S1046-2023(21)00019-0.

CAS Number

– 57817-83-1

Molecular Weight

– 295.29

Compound Purity

– 99.87

SMILES

– O[C@H]1[C@@H](OC)[C@H](N2C(N=CN=C3NC)=C3N=C2)O[C@@H]1CO

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Fat Mass and Obesity-associated Protein (FTO)

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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