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N4-Benzoyl-3′-O-DMT-2′-O-(2-methoxyethyl)-5-methylcytidine
SKU
HY-154441-Get quote
Category Oligonucleotides
Tags Cancer, Cell Cycle/DNA Damage, Nucleoside Antimetabolite/Analog
Products Details
Product Description
– N4-Benzoyl-3′-O-DMT-2′-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Web ID
– HY-154441
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C41H43N3O9
References
– [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
Molecular Weight
– 721.79
SMILES
– O=C1N=C(NC(C2=CC=CC=C2)=O)C(C)=CN1[C@@H]3O[C@@H]([C@H]([C@H]3OCCOC)OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)CO
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.