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N3-TFBA-O2Oc
$1,099
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Products Details
Product Description
– N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λmax=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers[1][2][3]. N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Web ID
– HY-151744
Shipping
– Room temperature
Molecular Formula
– C13H12F4N4O5
References
– [1]Morris JL, et al. Aryl azide photochemistry in defined protein environments. Org Lett. 2013 Feb 15;15(4):728-31. |[2]FLEET G, et al. Affinity Labelling of Antibodies with Aryl Nitrene as Reactive Group. Nature. 1969;224:511-512. |[3]Welle, et al. Tri- and tetravalent photoactivable cross-linking agents. Thieme. 2012;44(14):2249-2254.
CAS Number
– 1993119-45-1
Molecular Weight
– 380.25
SMILES
– [N-]=[N+]=NC1=C(C(F)=C(C(F)=C1F)C(NCCOCCOCC(O)=O)=O)F
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
