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Products Details
Product Description
– N2-iso-Butyroyl-7′-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Web ID
– HY-152988
Shipping
– Room temperature
Molecular Formula
– C35H38N6O6
References
– [1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
CAS Number
– 2243974-78-7
Molecular Weight
– 638.71
SMILES
– O=C(N=C(N1)NC(C(C)C)=O)C(N=C2)=C1N2[C@@H](CNC3)O[C@@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
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