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Products Details
Product Description
– N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Web ID
– HY-154235
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H47N5O6Si2
References
– [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
CAS Number
– 79974-70-2
Molecular Weight
– 581.85
SMILES
– OC[C@H]1O[C@@H](N(C=N2)C3=C2C(NC(NC(C(C)C)=O)=N3)=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Nucleoside Antimetabolite/Analog
Pathway
– Cell Cycle/DNA Damage
Product type
– Oligonucleotides
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