Download Files:
N-Desethyl amodiaquine dihydrochloride
$142 – $2,450
Products Details
Product Description
– N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine dihydrochloride can be used for the research of malaria[1][2].
Web ID
– HY-128554A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H20Cl3N3O
References
– [1]Xue-Qing Li, et al. Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate. J Pharmacol Exp Ther. 2002 Feb;300(2):399-407.|[2]Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82.
CAS Number
– 79049-30-2
Molecular Weight
– 400.73
Compound Purity
– 99.69
SMILES
– OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1CNCC.Cl.Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
