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N-Bromoacetyl-β-alanine
$300 – $540
Products Details
Product Description
– N-Bromoacetyl-β-alanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Web ID
– HY-141379
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C5H8BrNO3
References
– [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.|[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number
– 89520-11-6
Molecular Weight
– 210.03
SMILES
– O=C(O)CCNC(CBr)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– ADC Linker;PROTAC Linkers
Isoform
– Alkyl-Chain Linkers;Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
