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Products Details
Product Description
– N-Boc-SBP-0636457-OH is a synthesized E3 ligase ligand-linker conjugate that incorporates IAP ligand and a linker. N-Boc-SBP-0636457-OH can be used to design a PROTAC Bcl-xL degrader-1 (HY-131188)[1].
Web ID
– HY-131190
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H50N4O9
References
– [1]Zhang X, et al. Discovery of IAP-recruiting BCL-XL PROTACs as potent degraders across multiple cancer cell lines. Eur J Med Chem. 2020;199:112397.
Molecular Weight
– 658.78
SMILES
– O=C([C@@H]1C(C[C@@](N1C2=O)(OCC[C@@H]2NC([C@H](C)N(C(OC(C)(C)C)=O)C)=O)[H])(C)C)N[C@@H]3CCCC4=C3C=CC(OCCCC(O)=O)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– cIAP1
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
