N-Boc-SBP-0636457-O-C3-COOH

SKU HY-131190-Get quote Category Tags , ,

Products Details

Product Description

– N-Boc-SBP-0636457-OH is a synthesized E3 ligase ligand-linker conjugate that incorporates IAP ligand and a linker. N-Boc-SBP-0636457-OH can be used to design a PROTAC Bcl-xL degrader-1 (HY-131188)[1].

Web ID

– HY-131190

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C34H50N4O9

References

– [1]Zhang X, et al. Discovery of IAP-recruiting BCL-XL PROTACs as potent degraders across multiple cancer cell lines. Eur J Med Chem. 2020;199:112397.

Molecular Weight

– 658.78

SMILES

– O=C([C@@H]1C(C[C@@](N1C2=O)(OCC[C@@H]2NC([C@H](C)N(C(OC(C)(C)C)=O)C)=O)[H])(C)C)N[C@@H]3CCCC4=C3C=CC(OCCCC(O)=O)=C4

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– E3 Ligase Ligand-Linker Conjugates

Isoform

– cIAP1

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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