N-Boc-piperazine-C3-COOH

SKU HY-131184-Get quote Category Tags , ,

Products Details

Product Description

– N-Boc-piperazine-C3-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-N-piperazine-C3-COOH can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].

Web ID

– HY-131184

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C14H24N2O5

References

– [1]Cheng B, Ren Y, Cao H, Chen J. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

CAS Number

– 959053-53-3

Molecular Weight

– 300.35

SMILES

– O=C(O)CCCC(N1CCN(C(OC(C)(C)C)=O)CC1)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– PROTAC Linkers

Isoform

– Alkyl/ether Linkers

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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