Products Details

Product Description

– N-Arachidonyldopamine is a potent and selective endogenous CB1 receptor agonist with a Ki of 250 nM[1]. N-Arachidonyldopamine is also a potent and selective TRPV1 agonist an with EC50 of ~ 50 nM[2].

Web ID

– HY-110018

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C28H41NO3

References

– [1]Bisogno T, et al. N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo. Biochem J. 2000 Nov 1;351 Pt 3(Pt 3):817-24.|[2]Huang SM, et al. An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8400-5.

CAS Number

– 199875-69-9

Molecular Weight

– 439.63

SMILES

– CCCCC/C=CC/C=CC/C=CC/C=CCCCC(NCCC1=CC(O)=C(O)C=C1)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cannabinoid Receptor;TRP Channel

Isoform

– CB1;TRPV

Pathway

– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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