Download Files:
N-Arachidonyl maleimide
$116 – $800
Products Details
Product Description
– N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM[1].
Web ID
– HY-136562
Storage Temperature
– -80°C
Shipping
– Dry Ice
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C24H35NO2
References
– [1]Susanna M Saario, et al. Characterization of the Sulfhydryl-Sensitive Site in the Enzyme Responsible for Hydrolysis of 2-arachidonoyl-glycerol in Rat Cerebellar Membranes. Chem Biol. 2005 Jun;12(6):649-56.|[2]James J Burston, et al. N-arachidonyl Maleimide Potentiates the Pharmacological and Biochemical Effects of the Endocannabinoid 2-arachidonylglycerol Through Inhibition of Monoacylglycerol Lipase. J Pharmacol Exp Ther. 2008 Nov;327(2):546-53.
CAS Number
– 876305-42-9
Molecular Weight
– 369.54
Compound Purity
– 99.18
SMILES
– O=C(C=C1)N(CCCC/C=CC/C=CC/C=CC/C=CCCCCC)C1=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– MAGL
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
