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N-Arachidonoylserotonin
SKU
HY-103337-10mg (108.07 mM * 0.2 mL in methyl acetate)
Category Reference compound
Tags FAAH;TRP Channel, Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling, Neurological Disease
$115 – $600
Products Details
Product Description
– N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1].
Web ID
– HY-103337
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C30H42N2O2
References
– [1]Ortar G, et al. New N-arachidonoylserotonin analogues with potential “dual” mechanism of action against pain. J Med Chem. 2007;50(26):6554-6569.
CAS Number
– 187947-37-1
Molecular Weight
– 462.67
Compound Purity
– 98.0
SMILES
– CCCCC/C=CC/C=CC/C=CC/C=CCCCC(NCCC1=CNC2=C1C=C(O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– FAAH;TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
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