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(+)-N-Allylnormetazocine (hydrochloride)
$423 – $677
Products Details
Product Description
– (+)-N-Allylnormetazocine ((+)-SKF 10047) hydrochloride is a benzomorphan opioid with psychotomi metic effects. (+)-N-Allylnormetazocine hydrochloride is an opioid receptor antagonist with Ki values of 300 nM and 27 μM for σ1 and σ2 opioid receptors, respectively. (+)-N-Allylnormetazocine hydrochloride can be used for the research of neurological disease[1][2].
Web ID
– HY-101376
Shipping
– Room temperature
Molecular Formula
– C17H24ClNO
References
– [1]May EL, et al. Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2′-hydroxy-6,7-benzomorphan homologues. J Med Chem. 2000 Dec 28;43(26):5030-6.|[2]Brady KT, et al. Stereoisomers of N-allylnormetazocine: phencyclidine-like behavioral effects in squirrel monkeys and rats. Science. 1982 Jan 8;215(4529):178-80.
CAS Number
– 133005-41-1
Molecular Weight
– 293.83
SMILES
– C[C@@]1(CCN2CC=C)C3=CC(O)=CC=C3C[C@@]2([H])C1([H])C.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Opioid Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
