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N-Acetyldesloratadine
$135 – $480
Products Details
Product Description
– N-Acetyldesloratadine (SCH-37370) is a potent, orally active dual antagonist of platelet-activating factor (PAF) and histamine. N-Acetyldesloratadine inhibits PAF-induced aggregation of human platelets, with an IC50 of 0.6 µM[1].
Web ID
– HY-116120
Shipping
– Room temperature
Molecular Formula
– C21H21ClN2O
References
– [1]Billah MM, et, al. Discovery and preliminary pharmacology of Sch 37370, a dual antagonist of PAF and histamine. Lipids. 1991 Dec;26(12):1172-4.
CAS Number
– 117796-52-8
Molecular Weight
– 352.86
SMILES
– ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4CCN(CC4)C(C)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor;Platelet-activating Factor Receptor (PAFR)
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
