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Products Details
Product Description
– Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS). Nω-allyl-L-arginine can inactivate nNOS in a time-dependent manner. Nω-allyl-L-arginine also is a substrate, producing L-arginine, acrolein, and H2O[1][2].
Web ID
– HY-115750
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C9H18N4O2
References
– [1]Zhang HQ, et, al. Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by Nω-Allyl-l-Arginine. J. Am. Chem. Soc. 1997, 119, 45, 10888-10902.|[2]Hah JM, et, al. Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase. Bioorg Med Chem. 2000 Aug;8(8):1931-6.
CAS Number
– 139461-37-3
Molecular Weight
– 214.26
SMILES
– N[C@@H](CCCNC(NCC=C)=N)C(O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– NO Synthase
Isoform
– nNOS
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
