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Products Details
Product Description
– MV-1-NH-Me, the MV-1 based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER[1].
Web ID
– HY-111853
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C33H45N5O4
References
– [1]Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.
CAS Number
– 2095244-62-3
Molecular Weight
– 575.74
SMILES
– CNC([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC([C@H]3N(C([C@@H](NC([C@H](C)NC)=O)C4CCCCC4)=O)CCC3)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Isoform
– IAP
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
