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Mutant IDH1 inhibitor
SKU
HY-13972-10 mg
Category Reference compound
Tags Cancer, Isocitrate Dehydrogenase (IDH), Metabolic Enzyme/Protease
$205 – $1,800
Products Details
Product Description
– Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM.
Web ID
– HY-13972
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H34N6O3
References
– [1]3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404
CAS Number
– 1429180-08-4
Molecular Weight
– 466.58
Compound Purity
– 99.40
SMILES
– CC(C)[C@@H](COC1=O)N1C2=NC(N[C@@H](C)C3=CC=C(CN4CCN(C(C)=O)CC4)C=C3)=NC=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 34 mg/mL
Target
– Isocitrate Dehydrogenase (IDH)
Isoform
– IDH1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.