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Mutant EGFR inhibitor

$190$850

Products Details

Product Description

– Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M.

Web ID

– HY-13984

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C27H30ClN7O2

References

– [1]WO 2013014448 A1

CAS Number

– 1421373-62-7

Molecular Weight

– 520.03

Compound Purity

– 99.51

SMILES

– C=CC(NC1=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : ≥ 50 mg/mL

Target

– EGFR

Isoform

– EGFR/ErbB1/HER1

Pathway

– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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