Download Files:
Products Details
Product Description
– MurA-IN-3 is a reversible pyrrolidinedione-based MurA inhibitor. MurA-IN-3 has inhibitory activity for MurA with an IC50 value of 4.5 μM. MurA-IN-3 also has antibacterial activity[1].
Web ID
– HY-151875
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H23ClN2O5S
References
– [1]Reem K Fathalla, et al. Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA. J Med Chem. 2022 Nov 10;65(21):14740-14763.
CAS Number
– 2866186-38-9
Molecular Weight
– 523.00
SMILES
– CC1=CC=C2N=C(SC2=C1)N3C(C(O)=C(C3C4=CC=C(O4)C5=CC=C(C=C5)Cl)C(OC(C)(C)C)=O)=O
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
