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Products Details
Product Description
– MU380 is a potent and selective CHK1 inhibitor that induces apoptosis and has anticancer activity[1].
Web ID
– HY-112927
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C15H15BrF3N7
References
– [1]Miroslav Boudny, et al. Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells. Haematologica. 2019 Dec;104(12):2443-2455.Â
CAS Number
– 2109805-78-7
Molecular Weight
– 430.23
SMILES
– NC1=C(Br)C([C@H]2CNCCC2)=NC3=C(C4=CN(C(F)(F)F)N=C4)C=NN13
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Checkpoint Kinase (Chk)
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
