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Products Details
Product Description
– MtTMPK-IN-8 (compound 27) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor. MtTMPK-IN-8 has sub-micromolar activity against mycobacteria (MICs = 0.78~9.4 μM) without significant cytotoxicity. MtTMPK-IN-8 can be used for researching tuberculosis[1].
Web ID
– HY-146702
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H24N6O7
References
– [1]Jian Y, et al. Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents. Eur J Med Chem. 2020;206:112659.
Molecular Weight
– 508.48
SMILES
– CC1=CN(C(NC1=O)=O)C2CCN(CC2)C3=CC=C(C=C3)CNC(C4=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C4)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Thymidylate Synthase
Pathway
– Anti-infection;Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
