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Products Details
Product Description
– mTORC1-IN-2 (compound H3) is a NO donor compound that alleviates vasodilation and attenuates myocardial hypoxic injury. mTORC1-IN-2 upregulates TSC2-P expression and inhibits mTORC1 expression[1].
Web ID
– HY-155475
Shipping
– Room temperature
Molecular Formula
– C16H15N3O6
References
– [1]Yang W et al. Discovery of Efficient Hypoxia-Targeted NO Donor Compounds to Alleviate Hypoxia Cardiac Disease. J Med Chem. 2023 Nov 16.
CAS Number
– 2974368-96-0
Molecular Weight
– 345.31
SMILES
– O=NN(C)C1=CC=C(C=C1)OC(OCC2=C(C)C=C([N+]([O-])=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– mTOR
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
