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Products Details
Product Description
– MtInhA-IN-1 is a selective and orally active Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA) inhibitor with an IC50 of 0.23 μM. MtInhA-IN-1 potently against M. tuberculosis H37Rv strain with a MIC value of 0.4 μM[1].
Web ID
– HY-151941
Shipping
– Room temperature
Molecular Formula
– C21H22BrN3
References
– [1]Josiane Delgado Paz, et al. Novel 4-aminoquinolines: Synthesis, inhibition of the Mycobacterium tuberculosis enoyl-acyl carrier protein reductase, antitubercular activity, SAR, and preclinical evaluation. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114908.
Molecular Weight
– 396.32
SMILES
– CC1=NC2=C(C(NC3=CC=C(C=C3)N4CCCCC4)=C1)C=C(C=C2)Br
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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