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MSX-122

$92$726

Products Details

Product Description

– MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ∼10 nM. MSX-122 has anti-inflammatory and anti-metastatic activity.

Web ID

– HY-13696

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C16H16N6

References

– [1]Liang Z, et al. Development of a unique small molecule modulator of CXCR4. PLoS One. 2012;7(4):e34038.

CAS Number

– 897657-95-3

Molecular Weight

– 292.34

Compound Purity

– 98.92

SMILES

– C1(CNC2=NC=CC=N2)=CC=C(CNC3=NC=CC=N3)C=C1

Clinical Information

– Phase 1

Research Area

– Cancer; Inflammation/Immunology; Endocrinology

Solubility

– DMSO : 4 mg/mL (ultrasonic)

Target

– CXCR

Isoform

– CXCR4

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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