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Products Details
Product Description
– MS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice[1].
Web ID
– HY-114918
Shipping
– Room temperature
Molecular Formula
– C20H17F3N2O3
References
– [1]Latif R, et al. New small molecule agonists to the thyrotropin receptor. Thyroid. 2015 Jan;25(1):51-62.
CAS Number
– 512840-45-8
Molecular Weight
– 390.36
SMILES
– O=C(OCC1=CC=CC=C1)C2=C(NC(NC2C3=CC=C(C=C3)C(F)(F)F)=O)C
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– TSH Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
