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MreB Perturbing Compound A22 (hydrochloride)
$137 – $462
Products Details
Product Description
– MreB Perturbing Compound A22 hydrochloride is a benzylisothiourea compound that interacts with the ATP binding site of MreB rapidly and reversibly. MreB Perturbing Compound A22 hydrochloride blocks normal rod shape formation and inhibits chromosome partitioning in E. coli, inhibiting growth (MIC=3.1 µg/ml).
Web ID
– HY-118773
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C8H9Cl3N2S
References
– [1]Zemer Gitai, et al. MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell. 2005 Feb 11;120(3):329-41.|[2]Noritaka Iwai, et al. Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2. Biosci Biotechnol Biochem. 2002 Dec;66(12):2658-62.
CAS Number
– 22816-60-0
Molecular Weight
– 271.59
Compound Purity
– 99.0
SMILES
– ClC1=CC(CSC(N)=N)=CC=C1Cl.Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMF : ≥ 20 mg/mL|DMSO : ≥ 20 mg/mL|Ethanol : ≥ 1 mg/mL
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
