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Mps-BAY2a
SKU
HY-110242-10 mg
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton, Apoptosis;Mps1, Cancer
$350 – $2,680
Products Details
Product Description
– Mps-BAY2a is a monopolar spindle 1 (MPS1) inhibitor with an IC50 of 1 nM against human MPS1. Mps-BAY2a induces mitotic aberrations and apoptosis in cancer cells[1].
Web ID
– HY-110242
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H28N6O
References
– [1]Jemaà M, et al. Characterization of novel MPS1 inhibitors with preclinical anticancer activity. Cell Death Differ. 2013 Nov;20(11):1532-45.
CAS Number
– 1382477-96-4
Molecular Weight
– 476.57
Compound Purity
– 98.74
SMILES
– O=C(C1=CC=C(C2=CN=C3C(NCC(C)C)=NC(C4=C5C=CC=NC5=CC=C4)=CN32)C=C1)NC6CC6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Apoptosis;Mps1
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.