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Products Details
Product Description
– MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC500 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)[1].
Web ID
– HY-146651
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H11N5
References
– [1]Scott A Shaw, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg Med Chem. 2020 Nov 15;28(22):115723.
CAS Number
– 2088545-68-8
Molecular Weight
– 225.25
SMILES
– NC1=CC(CC2=CC=CC=C2)=C3N=NNC3=N1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Glutathione Peroxidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
