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MPI_5a
SKU
HY-113957-1 mg (16.7 mM * 200 μL in Acetonitrile)
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Epigenetics, HDAC
$340 – $1,010
Products Details
Product Description
– MPI_5a is a potent and selective HDAC6 inhibitor (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms. MPI_5a inhibits acyl-tubulin accumulation in cells with an IC50 value of 210 nM[1].
Web ID
– HY-113957
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H17N3O3
References
– [1]Blackburn C, et al. Potent histone deacetylase inhibitors derived from 4-(aminomethyl)-N-hydroxybenzamide with high selectivity for the HDAC6 isoform. J Med Chem. 2013 Sep 26;56(18):7201-11.
CAS Number
– 1259296-46-2
Molecular Weight
– 299.32
Compound Purity
– 99.0
SMILES
– O=C(C1=CC2=C(CN(C(C3=CC=CN3C)=O)CC2)C=C1)NO
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.