MPI-0479605

$156$1,596

Products Details

Product Description

– MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM.

Web ID

– HY-12660

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C22H29N7O

References

– [1]Tardif KD, et al. Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1. Mol Cancer Ther. 2011 Dec;10(12):2267-2275.

CAS Number

– 1246529-32-7

Molecular Weight

– 407.51

Compound Purity

– 99.51

SMILES

– CC(C=C(N1CCOCC1)C=C2)=C2NC3=NC4=C(N=CN4)C(NC5CCCCC5)=N3

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 11 mg/mL (ultrasonic;warming)

Target

– Apoptosis;Mps1

Pathway

– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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