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MPI-0479605
SKU
HY-12660-10 mg
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton, Apoptosis;Mps1, Cancer
$156 – $1,596
Products Details
Product Description
– MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM.
Web ID
– HY-12660
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H29N7O
References
– [1]Tardif KD, et al. Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1. Mol Cancer Ther. 2011 Dec;10(12):2267-2275.
CAS Number
– 1246529-32-7
Molecular Weight
– 407.51
Compound Purity
– 99.51
SMILES
– CC(C=C(N1CCOCC1)C=C2)=C2NC3=NC4=C(N=CN4)C(NC5CCCCC5)=N3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 11 mg/mL (ultrasonic;warming)
Target
– Apoptosis;Mps1
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.