Products Details

Product Description

– Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Web ID

– HY-128970

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C129H220N20O52S2

References

– [1]Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.

Molecular Weight

– 2947.36

SMILES

– O=C(N1CCC(NCCOCCOCCC(NCCNC(CCNC(OCC(OCCC(CO)OC(CO)OCCC(CO)OC(COC(NCCC(O)=O)=O)OCCC(CO)OC(COC(NCCC(NCCNC(CCOCCOCCNC(CCN2C(CC(C2=O)SCC(N)C(O)=O)=O)=O)=O)=O)=O)OCCC(CO)OC(COC(NCCC(N[C@H](C(OCCCNC([C@@H](NC([C@@H]([C@H]([C@@H]3N(CCC3)C(C[C@H]([C@H]([C@H](CC)C)N(C([C@@H](NC([C@H](C(C)C)N(C)C)=O)C(C)C)=O)C)OC)=O)OC)C)=O)CC4=CC=CC=C4)=O)=O)C)=O)=O)OC)OC(CO)CC)=O)=O)=O)=O)C(CC1=O)SC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Drug-Linker Conjugates for ADC

Isoform

– Non-cleavable Linker

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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