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MONNA
$110 – $550
Products Details
Product Description
– MONNA is a potent transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with an IC50 of 80 nM. MONNA induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions[1].
Web ID
– HY-100613
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C18H14N2O5
References
– [1]Oh SJ, et al. MONNA, a potent and selective blocker for transmembrane protein with unknown function 16/anoctamin-1. Mol Pharmacol. 2013 Nov;84(5):726-35.
CAS Number
– 1572936-83-4
Molecular Weight
– 338.31
Compound Purity
– 99.79
SMILES
– O=C(O)C1=CC([N+]([O-])=O)=CC=C1NC2=CC(OC)=C3C=CC=CC3=C2
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 55.56 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Chloride Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
