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Molidustat
$120 – $550
Products Details
Product Description
– Molidustat (BAY 85-3934) is a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with mean IC50 values of 480 nM for PHD1, 280 nM for PHD2, and 450 nM for PHD3.
Web ID
– HY-12654
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H14N8O2
References
– [1]Flamme I, et al. Mimicking hypoxia to treat anemia: HIF-stabilizer BAY 85-3934 (Molidustat) stimulates erythropoietin production without hypertensive effects. PLoS One. 2014 Nov 13;9(11):e111838.
CAS Number
– 1154028-82-6
Molecular Weight
– 314.30
Compound Purity
– 98.75
SMILES
– O=C1C(N2N=NC=C2)=CNN1C3=NC=NC(N4CCOCC4)=C3
Clinical Information
– Phase 3
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 5 mg/mL (ultrasonic)
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
