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Products Details
Product Description
– MNK/PIM-IN-1 represents an innovative dual MNK/PIM inhibitor with a good pharmacokinetic profile.
Web ID
– HY-132867
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H27FN6O2
References
– [1]Han Y, et al. Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth. J Med Chem. 2021 Sep 23;64(18):13719-13735.
CAS Number
– 2430792-91-7
Molecular Weight
– 486.54
SMILES
– O=C(C1=CC=C(C2=NC3=C(NC4=CC=C(F)C=C4OC(C)C)N=CN=C3C=C2)C=C1)N5CCNCC5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Pim
Pathway
– JAK/STAT Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
