Download Files:
MMV009085
$63 – $225
Products Details
Product Description
– MMV009085 is a potent PfHT1 (Plasmodium falciparum hexose transporter)-specific inhibitor and a potential anti-malarial agent . MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7)[1].
Web ID
– HY-153612
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C22H22N2O6
References
– [1]Xin Jiang, et al. Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum.Cell. 2020 Oct 1;183(1):258-268.e12.
CAS Number
– 298217-59-1
Molecular Weight
– 410.42
Compound Purity
– 95.0
SMILES
– O=C1C2=CC=C3C(N(CCCCO)C(C4=CC=C(C2=C34)C(N1CCCCO)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic)
Target
– GLUT;Parasite
Pathway
– Anti-infection;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
