Products Details

Product Description

– MmpL3-IN-3 (Compound 12) is a MmpL3 inhibitor. MmpL3-IN-3 shows a MIC of 0.1 μM against H37Rv. MmpL3-IN-3 shows good stability in mouse liver microsomes. MmpL3-IN-3 can be used for anti-tubercular research[1].

Web ID

– HY-149395

Shipping

– Room temperature

Molecular Formula

– C26H33ClN2Si

References

– [1]Vasudevan N, et al. Synthesis, biological evaluation and docking studies of silicon incorporated diarylpyrroles as MmpL3 inhibitors: An effective strategy towards development of potent anti-tubercular agents. Eur J Med Chem. 2023 Jul 16;259:115633.

CAS Number

– 1639438-67-7

Molecular Weight

– 437.09

SMILES

– CC1=C(CN2CC[Si](C)(C)CC2)C=C(C3=CC=C(Cl)C=C3)N1C4=CC=C(CC)C=C4

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Bacterial

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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